Endocrine Abstracts

Background: In the presence of specific symptoms and signs, Cushing’s syndrome (CS) may be easily recognised. On the other hand, in overweight and obese patients without typical features of CS, diagnosis may be omitted. Our aim was to evaluate the prevalence of CS among overweight and obese patients.Methods: We enrolled 264 overweight and obese patients who has not overt CS clinical features between January 2012 and December 2014 at Ankara Numune Ed...

Introduction: Gardner syndrome (GS) have very different extraintestinal manifestations such as include osteomas and thyroid cancers. Thyroid carcinomas associated with familial adenomatozis polyposis coli (FAP), are typically bilateral and multifocal. Our case presenting that GS included Graves’ disease (GD) and aggressive varyant of PTC.Case report: A 43-year-old men admitted to our out patient clinic for thyrotoxicosis investigation. He was compla...

Introduction: Endogenous Cushing’s syndrome (CS) results from chronic excessive cortisol secretion. Discovering the source of disease is very important, but non-invasive tests cannot always be enough at the determination of correct location. We need more novel markers for distinguishing adrenal Cushing (AC) and pituitary Cushing (CD). We conducted this study for evaluating usefullness of preoperative DHEA-S levels at differentiating AC and CD.Materi...

Introduction: Differentiated thyroid cancers (DTC) are the most frequently occuring endocrine malignancies. The factors determine the recurrences and metastases are whole body scanning (WBS) and either suppressed or stimulated thyroglobulin (sTg) levels. The aim of this study to evaluate the preablative factors predict of radioiodine remnant ablation (RRA) therapy success.Patients and methods: One hundred consecutive patients with DTC (94 papillary and s...

Aim: The aim of the present study was to evaluate the characteristic features of computerized tomography (CT) and magnetic resonance imaging (MRI) among functioning and non-functioning adrenal lesions.Materials and methods: We retrospectively reviewed the medical records of patients with adrenal mass. CT or MRI findings were available in 89 functioning and 148 non-functioning adrenal lesions (NFAL). Of the patients with functioning adrenal mass, 34 were ...

Introduction: Hypopituitarism is commonly acquired in adult life and its main causes are pituitary tumors and/or their treatments, empty sella syndrome and etc.Patients and methods: A double centre, cross-sectional database study was performed in Turkish population for last 10 years to investigate the etiology of hypopituitarism. One-hundred forty nine patients were included (53% female and 47% male) with a mean age of 47.9±15.6 years (ranging from ...

Introduction: It’s well known that any form of diabetes insipidus (DI) can be exacerbated or first become appearent during pregnancy, since increased catabolism of ADH by plasental vasopressinas enzyme. Postpartum DI cases mostly presenting as a part of Sheean syndrome and began after postpartum first days. There was no any published case of isolated DI that began in the 6th month after deliveration in current literature.Case: A 37...

Introduction: There are two clinical types of amiodarone induced thyrotoxicosis (AIT). Type I AIT appears with hyperthyroidism and type II with a destructive thyrotoxicosis. Treatment of type I AIT includes antithyroid drugs meanwhile type II needs steroids as the first line therapy. If there is no respond to medical treatment, surgical approach must be considered. Here in we present a type II AIT case who had no respond to combined therapy therefore treated with surgical appr...

Introduction: TURK-MEN study was carried out to evaluate the mutational analysis of so called sporadic MTC patients between 1994 and 2005. Our aim was to evaluate the ret genetic screening results, distribution of mutations among so called sporadic and hereditary MTC patients in Turkey between 2008 and 2012.Methods: Society of Endocrinology and Metabolism of Turkey (SEMT) sponsored ret genetic screening between July 2008 and January 2012 in 513 patients....